Melatonin: A Cure for Migraine?
September 21st, 2006 (Headache)
Melatonin is a hormone that is produced naturally in the pineal gland and dissipates as we grow older. It has been proposed as a migraine treatment by some because of its interaction with serotonin.
Melatonin may prove to be important in the treatment of migraine. One study showed improvement when melatonin tablets were given with a form of tension-type headache associated with a sleep disorder known as delayed sleep-phase syndrome. Another study revealed melatonin to be effective in preventing jet-lag symptoms.
It is known that melatonin interacts with multiple hormones and neurotransmitters and can alter one’s biorhythms. However, since there has not been any long-term studies that were conducted about the effect of melatonin in migraine, you should not take it on a regular basis. To date, melatonin has been more extensively studied in connection with sleep disorders than with migraine.