No matter where you work, you are the CEO of a one-person company: you. You aren’t a cog in the system; you are your own system. This is true whether you sling hams in a meat plant or you sell widgets or you are middle management.
Anything you really care about (that isn’t illegal) can be the foundation for a successful business. Passion about something makes you far more likely to succeed in your business venture.
If the foundation of a successful business is passion, then one of the major keys to success is creativity.